![]() This pathology was previously considered typical in developed countries, but nowadays it also shows a high prevalence in underdeveloped countries. Obesity is one of the most common nutritional problems worldwide, currently reaching epidemic proportions. ![]() In addition, the safety of the complement should be further studied. In conclusion, the results suggest that Garcinia-based supplements could be effective in short-term weight loss, although the data are not conclusive. Regarding safety, although Garcinia supplements have been revealed as safe in the vast majority of the studies carried out in animal models and humans, some cases of hepatotoxicity, serotonin toxicity and mania have been reported. While statistically significant weight loss was observed in some studies, no changes were found in others. Contradictory results have been observed regarding the effectiveness of the supplements. The aim of the present review is to gather reported data concerning the effectiveness of nutritional supplements based on Garcinia extracts on weight loss and their possible negative effects. The active principle of this plant to which these properties have been attributed, is hydroxycitric acid (HCA). Nutritional supplements to lose weight based on the Garcinia plant, specifically on Garcinia cambogia, are commonly used. In this context, nutritional supplements are presented as a therapeutic alternative to which more and more people are turning to. The prevalence of this pathology has increased in a worrying way over recent years, currently reaching epidemic proportions. ![]() Nowadays, obesity is one of the great nutritional problems facing public health. ![]()
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